Amiodarone Protocol Provides Cost-Effective Reduction in Postoperative Atrial Fibrillation

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Amiodarone for atrial fibrillation.

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Topical amiodarone during cardiac surgery: Does epicardial application of amiodarone prevent postoperative atrial fibrillation?

OBJECTIVES Atrial fibrillation (AF) is a common complication after cardiac surgery. Topical amiodarone on the epicardium may help prevent postoperative AF while avoiding the side effects of its systemic administration. The purpose of this study was to evaluate the all-comer strategy of epicardial amiodarone application for the prevention of postoperative AF. METHODS A retrospective observatio...

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Postoperative Atrial Fibrillation

Postoperative atrial fibrillation (POAF) is common among surgical patients and associated with a worse outcome. Pathophysiology of POAF is not fully disclosed, and several perioperative factors could be involved. Direct cardiac stimulation from perioperative use of catecholamines or increased sympathetic outflow from volume loss/anaemia/pain may play a role. Metabolic alterations, such as hypo-...

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Amiodarone versus sotalol for atrial fibrillation.

BACKGROUND The optimal pharmacologic means to restore and maintain sinus rhythm in patients with atrial fibrillation remains controversial. METHODS In this double-blind, placebo-controlled trial, we randomly assigned 665 patients who were receiving anticoagulants and had persistent atrial fibrillation to receive amiodarone (267 patients), sotalol (261 patients), or placebo (137 patients) and ...

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Considerations for the success of topical amiodarone to prevent postoperative atrial fibrillation.

600 The Journ one in the perioperative period prevents postoperative AF; however, its challenging side-effect profile limits its routine and widespread use as prophylaxis. It was therefore with great interest that we recently read the report by Feng and colleagues describing their success in applying a topical amiodarone-releasing hydrogel on the atrial surface during coronary artery bypass gra...

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ژورنال

عنوان ژورنال: The Annals of Thoracic Surgery

سال: 2018

ISSN: 0003-4975

DOI: 10.1016/j.athoracsur.2017.12.029